Genome Analysis Toolkit

Variant Discovery in High-Throughput Sequencing Data

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Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size. Learn more

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    Hello :),

    First of all, thank you very much for your precious work which helps me a lot in my daily life.

    I would like to know how you calculate the fractional coverage precisely. I have done a little bibliography but it is not really clear to me. 

    Thank you very much for the time you can give me. 


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