
Degang Wu
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How do I choose the "optimal" VQSR sensitivity threshold for indels?
For SNPs, we can choose the inflection point in the novel TiTv vs. sensitivity graph, but I have no idea what principle I should use when choosing the sensitivity threshold for indel.
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Best practice to deal with spanning deletion for downstream analysis
AnsweredHello everyone! I'm referring to this article on spanning deletion. Representing spanning deletion with * is good in itself, but unfortunately most of the downstream analysis tools I know cannot de...