Avatar

Dario

  • Total activity 9
  • Last activity
  • Member since
  • Following 0 users
  • Followed by 0 users
  • Votes 1
  • Subscriptions 4

Activity overview

Latest activity by Dario
  • Avatar

    Dario created a post,

    HaplotypeCaller's Underlying Statistical Model

    What statistical model does HaplotypeCaller use to decide between possible genotypes? In the simplest case of only a reference base and one alternate base at a position, I imagine something like a ...

  • Avatar

    Dario created a post,

    Implicit Assumption of Germline Short Variant Discovery

    Is an implicit assumption of the pipeline that the normal sample is far away enough from the tumour sample, such as a blood sample, so that cancer cells are not present at low levels? I have been s...

  • Avatar

    Dario created a post,

    Mutect for Somatic SNVs in Highly Polymorphic Genome Regions

    Answered

    Could there be a document created which carefully explains somatic SNV calling in regions where the reference genome sequence is not representative of what most people have? There is the clunky Pol...

  • Avatar

    Dario commented,

    Is there a table of filters containing detailed definitions of all of the possible ones in a document somewhere? The VCF header ones are too short for readers who weren't involved with the developm...