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Melcar Collodetti

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Latest activity by Melcar Collodetti
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    Melcar Collodetti commented,

    Our collaborators at the Intel-Broad Center for Genomic Data Engineering can provide you with recommended hardware configurations based on your planned usage. Let us know in the comment thread if y...

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    Melcar Collodetti commented,

    You're welcome.  Basically, what needs to be done is: -Fix the link to https://storage.googleapis.com/gatk-best-practices/somatic-b37/af-only-gnomad.raw.sites.vcf -Index the raw file with: gatk-4.2...

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    Melcar Collodetti commented,

    IT FINALLY WORKED:  ./gatk-4.2.6.1/gatk GetPileupSummaries \     --disable-sequence-dictionary-validation true \     -I amostra1_sorted_rmdup_F4.bam \     -V af-only-gnomad.raw.sites.vcf.1 \     -...

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    Melcar Collodetti commented,

    New try with GATK 4.2.2.0 and af-only-gnomad.raw.sites.vcf:  gatk-4.2.2.0/gatk IndexFeatureFile -I af-only-gnomad.raw.sites.vcf after index was done: ./gatk-4.2.2.0/gatk GetPileupSummaries \     -...

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    Melcar Collodetti commented,

    I also tried: wget https://storage.googleapis.com/gatk-best-practices/somatic-b37/af-only-gnomad.raw.sites.vcf bgzip af-only-gnomad.raw.sites.vcf bcftools index -t af-only-gnomad.raw.sites.vcf.gz  ...

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    Melcar Collodetti commented,

    I also tried the rename step that Field-Ye-Tian suggested (https://gatk.broadinstitute.org/hc/en-us/community/posts/360073450391-A-USER-ERROR-has-occurred-af-only-gnomad-hg38-vcf-gz-because-no-suit...

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    Melcar Collodetti commented,

    Changed GATK version to 4.2.6.1 and tried the following:  ./gatk-4.2.6.1/gatk GetPileupSummaries \     --disable-sequence-dictionary-validation true \     -I amostra1_sorted_rmdup_F4.bam \     -V ...

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    Melcar Collodetti created a post,

    af-only-gnomad.raw.sites.vcf

    Hello, GATK team I am using GATK 4.2.2.0 and trying to use af-only-gnomad.raw.sites.vcf (from GATK best-practices storage -> somaticb-37) as my germline resource for somatic analysis on the code:  ...