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Variant Discovery in High-Throughput Sequencing Data

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Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size. Learn more

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Show all All Planned Not planned Completed Answered No status Sort by newest post Newest post Recent activity Votes Comments
  • jar for mutect 1.1.7
    • Knight Ni
    • April 19, 2020 17:08
    1 vote 6 comments
  • Panel of Normals Documentation Answered
    • Ryan Gimple
    • April 16, 2020 17:48
    1 vote 16 comments
  • Cromwell GATK json list of files
    • Kristian Unger
    • April 16, 2020 07:41
    0 votes 3 comments
  • some Mito-mutations can't detected out right from amplicon data using Mutect2
    • rime
    • April 13, 2020 05:46
    0 votes 2 comments
  • problem with output from combinegvcf gatk 4.1.3
    • flaviarogerio
    • April 12, 2020 13:23
    0 votes 1 comment
  • Mutect2-exome-panel.vcf Not Found
    • Ryan Gimple
    • April 11, 2020 20:03
    0 votes 3 comments
  • GATK Runtime Error 3.8
    • Nicholas Cho Rui Wen
    • April 09, 2020 10:35
    0 votes 5 comments
  • multiple vcf files in FastaAlternateReferenceMaker
    • mk
    • April 09, 2020 04:59
    0 votes 3 comments
  • VariantFiltration Invalid Argument
    • mons7re
    • April 08, 2020 10:57
    0 votes 3 comments
  • GATK/Picard does not detect mates in paired-end BAM
    • jipvdinter
    • April 07, 2020 11:34
    • Edited
    1 vote 3 comments
  • GenotypeGVCFs: unexpected output in PGT and PID fields
    • Johnny Li
    • March 31, 2020 21:35
    • Edited
    0 votes 3 comments
  • picard test compile error
    • Kelly Swarts
    • March 30, 2020 19:34
    0 votes 1 comment
  • FilterByOrientationBias vanished in 4.1.6.0
    • riederd
    • March 30, 2020 11:41
    0 votes 11 comments
  • GenotypeGVCFs: java.lang.NullPointerException
    • Anze Staric
    • March 30, 2020 11:28
    0 votes 9 comments
  • GenomeSTRiP ReciprocalOverlapAnnotator Annotation track not sorted
    • Asma Riyaz
    • March 29, 2020 21:34
    • Edited
    0 votes 8 comments
  • Error using a edited gatk wdl (bam-unmapped-bam workflow) to accept array[files] as input rather than a single .bam file
    • sahuno
    • March 28, 2020 19:11
    0 votes 3 comments
  • Genome STRiP CNVDiscovery pipeline error
    • Beilei Bian
    • March 25, 2020 00:39
    0 votes 27 comments
  • Custom ReadFilter to ignore malformed reads ?
    • Yokofakun
    • March 21, 2020 13:26
    0 votes 2 comments
  • Picard ExtractIlluminaBarcodes return NullPointerException error
    • Jing Lin
    • March 20, 2020 21:52
    0 votes 4 comments
  • GATK4 HaplotypeCaller - read is malformed
    • Yi-Sian Lin
    • March 19, 2020 05:21
    • Edited
    0 votes 2 comments
  • Getting CNNScoreVariants to run faster
    • WVNicholson
    • March 18, 2020 16:29
    0 votes 3 comments
  • Broken GATK 3 documentation links
    • Harly Durbin
    • March 16, 2020 19:18
    0 votes 1 comment
  • HaplotypeCaller bam file path not recognized
    • Phillip Morin - NOAA Federal
    • March 13, 2020 18:42
    0 votes 7 comments
  • I want to know sequence_group_intervals in fivedollar-genome-anlalysis pipeline
    • BI_joy
    • March 11, 2020 08:53
    • Edited
    0 votes 1 comment
  • Do BQSR ignore VCF sites marked as filtered, or must they be removed from the file?
    • mk
    • March 11, 2020 00:37
    0 votes 4 comments
  • Dockerfile for genomes-in-the-cloud
    • Tony Bendis
    • March 10, 2020 05:16
    0 votes 5 comments
  • error java.lang.ClassCastException: java.lang.Long cannot be cast to java.lang.Byte
    • BI_joy
    • March 02, 2020 12:16
    0 votes 1 comment
  • CreateSomaticPanelOfNormals fails
    • Dieter Best
    • February 28, 2020 23:46
    0 votes 2 comments
  • Out of memory error using OpenJDK vs Oracle JDK for CNV-LOH
    • Jose Arcadio Buendia
    • February 28, 2020 01:53
    • Edited
    2 votes 2 comments
  • Why does my vcf contain a genotype when there are no reads supporting it?
    • Jeff Duty
    • February 27, 2020 14:51
    • Edited
    0 votes 3 comments
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