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Variant Discovery in High-Throughput Sequencing Data

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Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size. Learn more

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Show all All Planned Not planned Completed Answered No status Sort by votes Newest post Recent activity Votes Comments
  • Variable region not considered active region by HaplotypeCaller
    • Veronica
    • July 15, 2020 22:19
    0 votes 1 comment
  • Fatal error occuring during GATK4 PathSeqPipeline tool run
    • Jude Taylor
    • July 14, 2020 12:40
    0 votes 15 comments
  • FilterMutectCalls failing filters
    • Elizabeth Schabot
    • July 13, 2020 20:57
    0 votes 1 comment
  • WDL RNA-seq Hisat2
    • Thinh B. Vo
    • July 13, 2020 19:24
    0 votes 1 comment
  • How to execute workflow locally without docker
    • jiawei
    • July 11, 2020 15:28
    0 votes 1 comment
  • mitochondria_m2_wdl: MitochondriaPipeline Issues
    • Valentin
    • July 09, 2020 13:42
    0 votes 12 comments
  • RealignerTargetCreator
    • Madza Farias-Virgens
    • July 07, 2020 20:01
    0 votes 2 comments
  • Confusing GVCF results Answered
    • Yue Wang
    • July 07, 2020 14:31
    • Edited
    0 votes 1 comment
  • Extract individual samples from combined gvcf file
    • Balat
    • July 03, 2020 01:20
    0 votes 1 comment
  • Inquiry about the GATK Best Practices for variant calling on RNAseq
    • Benjamin Hing
    • July 02, 2020 00:24
    0 votes 1 comment
  • gatk3-register
    • touyupang
    • July 01, 2020 05:23
    0 votes 1 comment
  • How to reduce the processing time of BwaMemIndexImageCreator Answered
    • Ganesh P Kumar
    • June 25, 2020 07:10
    0 votes 2 comments
  • SelectVariants to get a vcf file with 1 individual from a vcf file with 3 individuals
    • Linda Do
    • June 22, 2020 21:46
    0 votes 3 comments
  • Picard LiftOverVCF 2.22.3. hs37d5_to_GRCh38. Many mismatched reference alleles
    • Argonaut44
    • June 23, 2020 18:09
    • Edited
    0 votes 3 comments
  • evaluation of the VCF file which is made using GATK Answered
    • behzad
    • June 22, 2020 11:41
    0 votes 2 comments
  • resource bundle b37
    • hirokomatsui
    • June 19, 2020 00:20
    0 votes 1 comment
  • MarkDuplicatesSparks not removing some duplicates?
    • Tom Morrison
    • June 18, 2020 14:55
    0 votes 15 comments
  • copyright issue
    • Özlem Okutman
    • June 16, 2020 13:17
    0 votes 2 comments
  • Genomestrip cannot find --ploidyMapFile
    • Swanthana Rekulapally
    • June 11, 2020 20:23
    0 votes 9 comments
  • IlluminaBasecallsToSam - barcode was not expected
    • Vincent Hahaut
    • June 10, 2020 19:04
    0 votes 1 comment
  • When will AnalyzeCovariates support R/4.0
    • Qi Yu
    • June 09, 2020 21:20
    0 votes 1 comment
  • Error when running FastaAlternateReferenceMaker
    • Fritz Forbang
    • June 09, 2020 10:27
    0 votes 1 comment
  • GenomicsDBImport does not recognize option --genomicsdb-update-workspace-path
    • Jose Luis Gualdron
    • June 08, 2020 08:08
    0 votes 2 comments
  • humanG1Kv37 to hg38 liftover issues
    • brian miller
    • June 06, 2020 00:44
    • Edited
    0 votes 3 comments
  • Error in running CollectGcBiasMetrics
    • SrivastavaS
    • June 05, 2020 17:30
    0 votes 1 comment
  • ReciprocalOverlapAnnotator error for Illumina data (both ERDS and CNVnator)
    • Ghausia Begum
    • June 04, 2020 04:22
    0 votes 5 comments
  • Mutect2: mitochondria mode weird
    • Roberto Sirica
    • June 03, 2020 14:46
    0 votes 2 comments
  • SelectVariants v4.1.6.0 doesn't select the variants as expected Answered
    • ABours
    • June 02, 2020 13:26
    0 votes 8 comments
  • VariantRecalibrator throwing VariantRecalibratorEngine - Evaluate datum returned a NaN warning then crashing with empty tranches file.
    • David Murphy
    • June 02, 2020 12:58
    • Edited
    0 votes 2 comments
  • something wrong with MarkDuplicatesSpark
    • charles_cai
    • June 02, 2020 10:09
    0 votes 1 comment
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