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Variant Discovery in High-Throughput Sequencing Data

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Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size. Learn more

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Show all All Planned Not planned Completed Answered No status Sort by newest post Newest post Recent activity Votes Comments
  • Running Genome STRiP SVPreprocess, but I got error message: "Invalid command line: Malformed walker argument: Could not find walker with name: ComputeInsertSizeHistogramsWalker"
    • Norio Tanaka
    • June 15, 2021 14:22
    0 votes 4 comments
  • Funcotator missing cDNA, Codon, and Protein Change for some chromosomes Answered
    • Robert Bremel
    • June 05, 2021 01:44
    0 votes 1 comment
  • Picard liftover Issue bostau8 to bostau6 Answered
    • Abrish
    • May 31, 2021 10:20
    0 votes 2 comments
  • GenomicsDBImport - A USER ERROR has occurred: Failed to create reader from file: 2.0
    • Jared Johnson
    • May 07, 2021 20:44
    0 votes 1 comment
  • DepthOfCoverage with -gene-list and readgroup as --partition-type options Answered
    • David Jaspez
    • May 06, 2021 14:58
    0 votes 7 comments
  • sample_gender.report.txt is empty when running SVpreprocess restricted to chromosomes
    • zzq
    • April 16, 2021 11:52
    • Edited
    0 votes 8 comments
  • How do I keep a glob from copying a file in Cromwell / WDL
    • Gregory Dougherty
    • March 09, 2021 00:24
    0 votes 1 comment
  • ApplyBQSR no positional argument is defined for this tool Answered
    • Jose Aragon
    • March 06, 2021 14:26
    0 votes 7 comments
  • How to Fix the follow ValidateSamFile error ?
    • Luis Enrique Romero Cruz
    • March 06, 2021 03:51
    0 votes 1 comment
  • BaseRecalibrator on MT .bam files
    • Sharon Cox
    • February 19, 2021 09:48
    • Edited
    0 votes 1 comment
  • LiftoverVcf: hg19 to hg38 all variants mismatched
    • Ken Hanscombe
    • February 17, 2021 14:13
    0 votes 3 comments
  • Error when trying to generate the second recalibration table for AnalyzeCovariates
    • ISmolicz
    • February 17, 2021 12:03
    0 votes 10 comments
  • Checking ReadGroup name in BAM file with GATK instructions
    • Julianne Radford
    • February 16, 2021 19:04
    0 votes 1 comment
  • How to work with CNN variant caller
    • Danio Rerio
    • February 16, 2021 16:09
    0 votes 3 comments
  • Mitochondrial analysis - FilterMutectCalls autosomal-coverage is not an option Answered
    • leory
    • February 16, 2021 13:42
    0 votes 3 comments
  • HaplotypeCaller and Read Group Errors
    • Julianne Radford
    • February 11, 2021 17:45
    0 votes 1 comment
  • DepthOfCoverage Error: Refseq file contains transcripts with zero coding length
    • ashgorden
    • February 04, 2021 08:15
    0 votes 2 comments
  • filterSamReads stdout format error
    • rcorbett
    • February 04, 2021 15:31
    • Edited
    0 votes 15 comments
  • Cromwell stuck at WaitingForReturnCode on Mac
    • Marc Crepeau
    • February 01, 2021 21:00
    0 votes 3 comments
  • Reference Fasta vs Alt Reference Fasta
    • Linda Do
    • January 29, 2021 21:56
    0 votes 2 comments
  • Mutect2: NuMTs filtering on RNA-seq Answered
    • Leore Nehemie Bensabath
    • January 29, 2021 15:57
    0 votes 2 comments
  • HaplotypeCaller -ERC GVCF -variant_index_type LINEAR
    • Matilde
    • January 22, 2021 18:22
    1 vote 1 comment
  • Why do I see difference in ploidy in GT field within same sample after GenotypeVCFs
    • Emila Mańko
    • January 21, 2021 17:54
    0 votes 3 comments
  • Comparison between ReadsPipelineSpark and MarkDuplicates
    • AMN
    • January 20, 2021 00:36
    • Edited
    0 votes 7 comments
  • Resource bundle for GRCh37
    • Reda
    • January 17, 2021 17:38
    0 votes 2 comments
  • Funcotator missing AF
    • Haiying Kong
    • January 11, 2021 15:13
    0 votes 1 comment
  • MarkDuplicates
    • JAY SINGH
    • January 10, 2021 13:41
    0 votes 1 comment
  • ASEReadCounter java.lang.ArrayIndexOutOfBoundsException: 0
    • zhaol
    • January 08, 2021 07:38
    0 votes 3 comments
  • Any documents for 199 columns in Funcotator output?
    • Haiying Kong
    • January 07, 2021 10:03
    0 votes 2 comments
  • When the useful PGT and PID fields have been implemented in GATK tool for the first time
    • Sandrine lagarrigue
    • December 31, 2020 17:36
    0 votes 1 comment
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