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Variant Discovery in High-Throughput Sequencing Data

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Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size. Learn more

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Somatic

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Show all All Planned Not planned Completed Answered No status Sort by newest post Newest post Recent activity Votes Comments
  • FilterMutectCalls chokes on infinite POPAF produced by Mutect2 Answered
    • Eric Blanc
    • January 28, 2020 13:09
    0 votes 10 comments
  • CreateReadCountPanelOfNormals doesn't finish because java.lang.OutOfMemoryError
    • Akshay Sanghi
    • January 28, 2020 03:45
    0 votes 6 comments
  • Smoothing noisy tumor-only CNV data?
    • Kate Megquier
    • January 24, 2020 02:19
    0 votes 3 comments
  • Allelic fraction NaNs in CNV pipeline
    • Kate Megquier
    • January 24, 2020 01:24
    0 votes 1 comment
  • Funcotator maf output problems on Varscan2 vcf files
    • A. Brink
    • January 23, 2020 17:53
    0 votes 10 comments
  • BaseRecalibrator takes forever to run. Any suggestions?
    • Matvei Khoroshkin
    • January 21, 2020 22:37
    0 votes 3 comments
  • calling Multi-allelic single nucleotide variants with mutect2
    • paruchuri anoosha
    • January 21, 2020 21:18
    0 votes 1 comment
  • Funcotator error: StringIndexOutOfBoundsException Answered
    • lck
    • January 21, 2020 14:41
    0 votes 6 comments
  • CNV pipeline not plotting all segments - PlotModeledSegments
    • Taylor Falk
    • January 17, 2020 15:13
    0 votes 2 comments
  • Mutect2 - Need one or two reads to construct a fragment
    • D B
    • January 17, 2020 14:43
    0 votes 13 comments
  • Mutect2 miscalls AF and AD of EGFR G719S on a reference sample, and FilterMutectCalls flags it with "strand bias"
    • mack812
    • January 16, 2020 08:00
    0 votes 6 comments
  • mutect2 calls if one of the samples have low coverage? filtering?
    • Naveen Ramesh
    • January 15, 2020 22:55
    0 votes 4 comments
  • Segmentation fault when using GenomicsDBImport to create a panel of normals
    • Mark Welsh
    • January 15, 2020 14:43
    0 votes 8 comments
  • Somatic pipeline from FASTQ to VCF
    • Maxime
    • January 14, 2020 14:53
    0 votes 2 comments
  • Call germline mutations from Mutect2
    • Chadi Saad
    • January 14, 2020 10:30
    1 vote 3 comments
  • docker CreateReadCountPanelOfNormals cblas_dspr error
    • zhao shilin
    • January 09, 2020 10:29
    0 votes 10 comments
  • Missing link for TCGA WGS bam files on FireCloud
    • Yiyun Rao
    • January 08, 2020 20:15
    0 votes 1 comment
  • GatherVcfs error.
    • MatthewP
    • January 08, 2020 03:10
    0 votes 1 comment
  • CollectGcBiasMetrics Array Index Out Of Bounds Exception
    • Andrey Koch
    • January 08, 2020 01:53
    0 votes 3 comments
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