python exited with 135 in germlinecnvcaller
Dear GATK team,
hi. now I am discovering for pathogenic CNV via GATK germline CNV pipelin.
Previously, I analyzed the other cohort and pipeline worked well.
However, I faced with the following error, even though it was at the same environment and setting.
Is it problem with size of memory in my machine?
If you have any advices to solved this, can you tell it to me?
Additionally, is there any options for GermlineCNVcaller to specify the number of cores or threads to use?
Best,
Shun
a) GATK version used:
4.2.5.0
b) Exact command used:
/home/inos0304/modules/gatk-4.2.5.0/gatk GermlineCNVCaller --run-mode COHORT -L /home/inos0304/human_genome_analysis/cnv/analysis_female/scatter/temp_0001_of_41/scattered.interval_list -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_04.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_13.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_17.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_20.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_23.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_24.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_25.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_27.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_29.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_30.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_31.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_32.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_36.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_41.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_47.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_49.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_56.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_59.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_60.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_64.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_67.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_68.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_85.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_86.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_05.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_07.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_09.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_18.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_20.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_28.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_32.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_34.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_35.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_39.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_41.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_44.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_50.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_56.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_57.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_59.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_63.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_73.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_78.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_92.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_95.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_07.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_15.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_16.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_23.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_25.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_31.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_37.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_43.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_45.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_46.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_48.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_50.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_56.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_58.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_60.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_03.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_11.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_16.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_17.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_21.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_23.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_29.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_30.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_33.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_34.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_41.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_43.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_52.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_55.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_58.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_61.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_73.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_77.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_90.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_96.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_02.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_07.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_09.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_10.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_11.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_12.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_19.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_21.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_23.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_26.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_28.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_29.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_30.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_32.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_35.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_39.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_40.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_42.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_45.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_46.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_62.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_65.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_80.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_91.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_93.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_06.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_20.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_28.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_29.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_37.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_39.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_46.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_50.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_53.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_58.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_60.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_61.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_65.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_71.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_81.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_82.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_83.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_87.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_90.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_91.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_01.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_08.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_11.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_13.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_18.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_20.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_23.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_24.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_25.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_27.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_28.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_29.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_31.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_34.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_35.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_46.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_48.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_51.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_52.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_55.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_58.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_63.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_65.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_66.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_67.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_69.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_70.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_74.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_75.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_76.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_77.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_78.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_82.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_85.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_86.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_91.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_92.tsv -I /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_93.tsv --contig-ploidy-calls /home/inos0304/human_genome_analysis/cnv/analysis_female/ploidy-calls --annotated-intervals /home/inos0304/human_genome_analysis/cnv/exome.annotated.tsv --interval-merging-rule OVERLAPPING_ONLY --output /home/inos0304/human_genome_analysis/cnv/analysis_female/cohort_female --output-prefix cohort_female_01 --verbosity DEBUG
c) Entire program log:Picked up JAVA_TOOL_OPTIONS: -XX:+UseSerialGC -Xmx6g -Xms6g
12:52:02.720 INFO NativeLibraryLoader - Loading libgkl_compression.so from jar:file:/rshare1/ZETTAI_path_WA_slash_home_KARA/home/inos0304/modules/gatk-4.2.5.0/gatk-package-4.2.5.0-local.jar!/com/intel/gkl/native/libgkl_compression.so
12:52:02.754 DEBUG NativeLibraryLoader - Extracting libgkl_compression.so to /tmp/libgkl_compression6881354295017338112.so
Apr 22, 2022 12:52:02 PM shaded.cloud_nio.com.google.auth.oauth2.ComputeEngineCredentials runningOnComputeEngine
INFO: Failed to detect whether we are running on Google Compute Engine.
12:52:02.938 INFO GermlineCNVCaller - ------------------------------------------------------------
12:52:02.938 INFO GermlineCNVCaller - The Genome Analysis Toolkit (GATK) v4.2.5.0
12:52:02.938 INFO GermlineCNVCaller - For support and documentation go to https://software.broadinstitute.org/gatk/
12:52:02.939 INFO GermlineCNVCaller - Executing as inos0304@rc018i on Linux v4.18.0-348.12.2.el8_5.x86_64 amd64
12:52:02.939 INFO GermlineCNVCaller - Java runtime: Java HotSpot(TM) 64-Bit Server VM v1.8.0_181-b13
12:52:02.939 INFO GermlineCNVCaller - Start Date/Time: 2022/04/22 12:52:02 JST
12:52:02.939 INFO GermlineCNVCaller - ------------------------------------------------------------
12:52:02.939 INFO GermlineCNVCaller - ------------------------------------------------------------
12:52:02.940 INFO GermlineCNVCaller - HTSJDK Version: 2.24.1
12:52:02.940 INFO GermlineCNVCaller - Picard Version: 2.25.4
12:52:02.940 INFO GermlineCNVCaller - Built for Spark Version: 2.4.5
12:52:02.941 INFO GermlineCNVCaller - HTSJDK Defaults.BUFFER_SIZE : 131072
12:52:02.941 INFO GermlineCNVCaller - HTSJDK Defaults.COMPRESSION_LEVEL : 2
12:52:02.941 INFO GermlineCNVCaller - HTSJDK Defaults.CREATE_INDEX : false
12:52:02.941 INFO GermlineCNVCaller - HTSJDK Defaults.CREATE_MD5 : false
12:52:02.941 INFO GermlineCNVCaller - HTSJDK Defaults.CUSTOM_READER_FACTORY :
12:52:02.941 INFO GermlineCNVCaller - HTSJDK Defaults.DISABLE_SNAPPY_COMPRESSOR : false
12:52:02.941 INFO GermlineCNVCaller - HTSJDK Defaults.EBI_REFERENCE_SERVICE_URL_MASK : https://www.ebi.ac.uk/ena/cram/md5/%s
12:52:02.941 INFO GermlineCNVCaller - HTSJDK Defaults.NON_ZERO_BUFFER_SIZE : 131072
12:52:02.941 INFO GermlineCNVCaller - HTSJDK Defaults.REFERENCE_FASTA : null
12:52:02.941 INFO GermlineCNVCaller - HTSJDK Defaults.SAM_FLAG_FIELD_FORMAT : DECIMAL
12:52:02.941 INFO GermlineCNVCaller - HTSJDK Defaults.USE_ASYNC_IO_READ_FOR_SAMTOOLS : false
12:52:02.941 INFO GermlineCNVCaller - HTSJDK Defaults.USE_ASYNC_IO_WRITE_FOR_SAMTOOLS : true
12:52:02.941 INFO GermlineCNVCaller - HTSJDK Defaults.USE_ASYNC_IO_WRITE_FOR_TRIBBLE : false
12:52:02.942 INFO GermlineCNVCaller - HTSJDK Defaults.USE_CRAM_REF_DOWNLOAD : false
12:52:02.942 DEBUG ConfigFactory - Configuration file values:
12:52:02.944 DEBUG ConfigFactory - gcsMaxRetries = 20
12:52:02.944 DEBUG ConfigFactory - gcsProjectForRequesterPays =
12:52:02.944 DEBUG ConfigFactory - gatk_stacktrace_on_user_exception = false
12:52:02.944 DEBUG ConfigFactory - samjdk.use_async_io_read_samtools = false
12:52:02.944 DEBUG ConfigFactory - samjdk.use_async_io_write_samtools = true
12:52:02.944 DEBUG ConfigFactory - samjdk.use_async_io_write_tribble = false
12:52:02.944 DEBUG ConfigFactory - samjdk.compression_level = 2
12:52:02.945 DEBUG ConfigFactory - spark.kryoserializer.buffer.max = 512m
12:52:02.945 DEBUG ConfigFactory - spark.driver.maxResultSize = 0
12:52:02.945 DEBUG ConfigFactory - spark.driver.userClassPathFirst = true
12:52:02.945 DEBUG ConfigFactory - spark.io.compression.codec = lzf
12:52:02.945 DEBUG ConfigFactory - spark.executor.memoryOverhead = 600
12:52:02.945 DEBUG ConfigFactory - spark.driver.extraJavaOptions =
12:52:02.945 DEBUG ConfigFactory - spark.executor.extraJavaOptions =
12:52:02.945 DEBUG ConfigFactory - codec_packages = [htsjdk.variant, htsjdk.tribble, org.broadinstitute.hellbender.utils.codecs]
12:52:02.945 DEBUG ConfigFactory - read_filter_packages = [org.broadinstitute.hellbender.engine.filters]
12:52:02.945 DEBUG ConfigFactory - annotation_packages = [org.broadinstitute.hellbender.tools.walkers.annotator]
12:52:02.945 DEBUG ConfigFactory - cloudPrefetchBuffer = 40
12:52:02.945 DEBUG ConfigFactory - cloudIndexPrefetchBuffer = -1
12:52:02.945 DEBUG ConfigFactory - createOutputBamIndex = true
12:52:02.945 INFO GermlineCNVCaller - Deflater: IntelDeflater
12:52:02.945 INFO GermlineCNVCaller - Inflater: IntelInflater
12:52:02.945 INFO GermlineCNVCaller - GCS max retries/reopens: 20
12:52:02.945 INFO GermlineCNVCaller - Requester pays: disabled
12:52:02.946 INFO GermlineCNVCaller - Initializing engine
12:52:02.948 DEBUG ScriptExecutor - Executing:
12:52:02.948 DEBUG ScriptExecutor - python
12:52:02.948 DEBUG ScriptExecutor - -c
12:52:02.948 DEBUG ScriptExecutor - import gcnvkernel
12:53:49.009 DEBUG ScriptExecutor - Result: 0
12:53:49.010 INFO GermlineCNVCaller - Done initializing engine
12:53:53.493 INFO GermlineCNVCaller - Intervals specified...
12:53:53.858 DEBUG GenomeLocParser - Prepared reference sequence contig dictionary
12:53:53.858 DEBUG GenomeLocParser - chr1 (248956422 bp)
12:53:53.858 DEBUG GenomeLocParser - chr2 (242193529 bp)
12:53:53.858 DEBUG GenomeLocParser - chr3 (198295559 bp)
12:53:53.858 DEBUG GenomeLocParser - chr4 (190214555 bp)
12:53:53.858 DEBUG GenomeLocParser - chr5 (181538259 bp)
12:53:53.858 DEBUG GenomeLocParser - chr6 (170805979 bp)
12:53:53.859 DEBUG GenomeLocParser - chr7 (159345973 bp)
12:53:53.859 DEBUG GenomeLocParser - chr8 (145138636 bp)
12:53:53.859 DEBUG GenomeLocParser - chr9 (138394717 bp)
12:53:53.859 DEBUG GenomeLocParser - chr10 (133797422 bp)
12:53:53.859 DEBUG GenomeLocParser - chr11 (135086622 bp)
12:53:53.859 DEBUG GenomeLocParser - chr12 (133275309 bp)
12:53:53.859 DEBUG GenomeLocParser - chr13 (114364328 bp)
12:53:53.859 DEBUG GenomeLocParser - chr14 (107043718 bp)
12:53:53.859 DEBUG GenomeLocParser - chr15 (101991189 bp)
12:53:53.859 DEBUG GenomeLocParser - chr16 (90338345 bp)
12:53:53.859 DEBUG GenomeLocParser - chr17 (83257441 bp)
12:53:53.859 DEBUG GenomeLocParser - chr18 (80373285 bp)
12:53:53.859 DEBUG GenomeLocParser - chr19 (58617616 bp)
12:53:53.859 DEBUG GenomeLocParser - chr20 (64444167 bp)
12:53:53.859 DEBUG GenomeLocParser - chr21 (46709983 bp)
12:53:53.859 DEBUG GenomeLocParser - chr22 (50818468 bp)
12:53:53.859 DEBUG GenomeLocParser - chrX (156040895 bp)
12:53:53.860 DEBUG GenomeLocParser - chrY (57227415 bp)
12:53:53.860 DEBUG GenomeLocParser - chrM (16569 bp)
12:53:53.860 DEBUG GenomeLocParser - chrEBV (171823 bp)
12:53:53.860 DEBUG GenomeLocParser - decoy (6391639 bp)
12:53:54.283 INFO FeatureManager - Using codec IntervalListCodec to read file file:///home/inos0304/human_genome_analysis/cnv/analysis_female/scatter/temp_0001_of_41/scattered.interval_list
12:53:54.425 DEBUG FeatureDataSource - Cache statistics for FeatureInput /home/inos0304/human_genome_analysis/cnv/analysis_female/scatter/temp_0001_of_41/scattered.interval_list:/home/inos0304/human_genome_analysis/cnv/analysis_female/scatter/temp_0001_of_41/scattered.interval_list:
12:53:54.425 DEBUG FeatureCache - Cache hit rate was 0.00% (0 out of 0 total queries)
12:53:54.430 INFO IntervalArgumentCollection - Processing 2938994 bp from intervals
12:53:54.446 INFO GermlineCNVCaller - Reading and validating annotated intervals...
12:53:54.878 WARN GermlineCNVCaller - Sequence dictionary in annotated-intervals file does not match the master sequence dictionary.
12:53:54.894 INFO GermlineCNVCaller - GC-content annotations for intervals found; explicit GC-bias correction will be performed...
12:53:54.930 INFO GermlineCNVCaller - Running the tool in COHORT mode...
12:53:54.930 INFO GermlineCNVCaller - Validating and aggregating data from input read-count files...
12:53:54.930 DEBUG GenomeLocParser - Prepared reference sequence contig dictionary
12:53:54.930 DEBUG GenomeLocParser - chr1 (248956422 bp)
12:53:54.930 DEBUG GenomeLocParser - chr2 (242193529 bp)
12:53:54.930 DEBUG GenomeLocParser - chr3 (198295559 bp)
12:53:54.930 DEBUG GenomeLocParser - chr4 (190214555 bp)
12:53:54.930 DEBUG GenomeLocParser - chr5 (181538259 bp)
12:53:54.930 DEBUG GenomeLocParser - chr6 (170805979 bp)
12:53:54.930 DEBUG GenomeLocParser - chr7 (159345973 bp)
12:53:54.931 DEBUG GenomeLocParser - chr8 (145138636 bp)
12:53:54.931 DEBUG GenomeLocParser - chr9 (138394717 bp)
12:53:54.931 DEBUG GenomeLocParser - chr10 (133797422 bp)
12:53:54.931 DEBUG GenomeLocParser - chr11 (135086622 bp)
12:53:54.931 DEBUG GenomeLocParser - chr12 (133275309 bp)
12:53:54.931 DEBUG GenomeLocParser - chr13 (114364328 bp)
12:53:54.931 DEBUG GenomeLocParser - chr14 (107043718 bp)
12:53:54.931 DEBUG GenomeLocParser - chr15 (101991189 bp)
12:53:54.931 DEBUG GenomeLocParser - chr16 (90338345 bp)
12:53:54.931 DEBUG GenomeLocParser - chr17 (83257441 bp)
12:53:54.931 DEBUG GenomeLocParser - chr18 (80373285 bp)
12:53:54.931 DEBUG GenomeLocParser - chr19 (58617616 bp)
12:53:54.931 DEBUG GenomeLocParser - chr20 (64444167 bp)
12:53:54.931 DEBUG GenomeLocParser - chr21 (46709983 bp)
12:53:54.931 DEBUG GenomeLocParser - chr22 (50818468 bp)
12:53:54.931 DEBUG GenomeLocParser - chrX (156040895 bp)
12:53:54.931 DEBUG GenomeLocParser - chrY (57227415 bp)
12:53:54.931 DEBUG GenomeLocParser - chrM (16569 bp)
12:53:54.931 DEBUG GenomeLocParser - chrEBV (171823 bp)
12:53:54.932 DEBUG GenomeLocParser - decoy (6391639 bp)
12:53:54.940 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_04.tsv (1 / 163)
12:53:55.166 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_13.tsv (2 / 163)
12:53:55.440 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_17.tsv (3 / 163)
12:53:55.723 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_20.tsv (4 / 163)
12:53:55.968 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_23.tsv (5 / 163)
12:53:56.197 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_24.tsv (6 / 163)
12:53:56.405 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_25.tsv (7 / 163)
12:53:56.617 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_27.tsv (8 / 163)
12:53:57.033 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_29.tsv (9 / 163)
12:53:57.228 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_30.tsv (10 / 163)
12:53:57.434 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_31.tsv (11 / 163)
12:53:57.654 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_32.tsv (12 / 163)
12:53:57.845 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_36.tsv (13 / 163)
12:53:58.061 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_41.tsv (14 / 163)
12:53:58.292 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_47.tsv (15 / 163)
12:53:58.499 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_49.tsv (16 / 163)
12:53:58.693 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_56.tsv (17 / 163)
12:53:58.904 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_59.tsv (18 / 163)
12:53:59.115 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_60.tsv (19 / 163)
12:53:59.321 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_64.tsv (20 / 163)
12:53:59.521 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_67.tsv (21 / 163)
12:53:59.712 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_68.tsv (22 / 163)
12:53:59.913 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_85.tsv (23 / 163)
12:54:00.128 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/HN7448_86.tsv (24 / 163)
12:54:00.387 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_05.tsv (25 / 163)
12:54:00.614 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_07.tsv (26 / 163)
12:54:00.831 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_09.tsv (27 / 163)
12:54:01.056 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_18.tsv (28 / 163)
12:54:01.251 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_20.tsv (29 / 163)
12:54:01.468 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_28.tsv (30 / 163)
12:54:01.719 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_32.tsv (31 / 163)
12:54:02.025 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_34.tsv (32 / 163)
12:54:02.320 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_35.tsv (33 / 163)
12:54:02.517 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_39.tsv (34 / 163)
12:54:02.750 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_41.tsv (35 / 163)
12:54:02.948 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_44.tsv (36 / 163)
12:54:03.156 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_50.tsv (37 / 163)
12:54:03.356 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_56.tsv (38 / 163)
12:54:03.546 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_57.tsv (39 / 163)
12:54:03.743 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_59.tsv (40 / 163)
12:54:03.978 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_63.tsv (41 / 163)
12:54:04.182 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_73.tsv (42 / 163)
12:54:04.384 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_78.tsv (43 / 163)
12:54:04.590 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_92.tsv (44 / 163)
12:54:04.784 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/JN6556_95.tsv (45 / 163)
12:54:04.982 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_07.tsv (46 / 163)
12:54:05.168 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_15.tsv (47 / 163)
12:54:05.346 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_16.tsv (48 / 163)
12:54:05.546 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_23.tsv (49 / 163)
12:54:05.750 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_25.tsv (50 / 163)
12:54:05.938 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_31.tsv (51 / 163)
12:54:06.379 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_37.tsv (52 / 163)
12:54:06.589 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_43.tsv (53 / 163)
12:54:06.785 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_45.tsv (54 / 163)
12:54:06.981 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_46.tsv (55 / 163)
12:54:07.173 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_48.tsv (56 / 163)
12:54:07.382 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_50.tsv (57 / 163)
12:54:07.560 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_56.tsv (58 / 163)
12:54:07.757 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_58.tsv (59 / 163)
12:54:07.939 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4100_60.tsv (60 / 163)
12:54:08.115 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_03.tsv (61 / 163)
12:54:08.333 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_11.tsv (62 / 163)
12:54:08.515 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_16.tsv (63 / 163)
12:54:08.699 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_17.tsv (64 / 163)
12:54:08.892 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_21.tsv (65 / 163)
12:54:09.112 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_23.tsv (66 / 163)
12:54:09.309 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_29.tsv (67 / 163)
12:54:09.492 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_30.tsv (68 / 163)
12:54:09.679 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_33.tsv (69 / 163)
12:54:09.881 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_34.tsv (70 / 163)
12:54:10.075 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_41.tsv (71 / 163)
12:54:10.274 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_43.tsv (72 / 163)
12:54:10.467 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_52.tsv (73 / 163)
12:54:10.869 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_55.tsv (74 / 163)
12:54:11.060 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_58.tsv (75 / 163)
12:54:11.254 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_61.tsv (76 / 163)
12:54:11.587 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_73.tsv (77 / 163)
12:54:11.766 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_77.tsv (78 / 163)
12:54:11.972 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_90.tsv (79 / 163)
12:54:12.171 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4213_96.tsv (80 / 163)
12:54:12.380 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_02.tsv (81 / 163)
12:54:12.590 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_07.tsv (82 / 163)
12:54:12.783 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_09.tsv (83 / 163)
12:54:12.987 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_10.tsv (84 / 163)
12:54:13.191 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_11.tsv (85 / 163)
12:54:13.384 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_12.tsv (86 / 163)
12:54:13.957 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_19.tsv (87 / 163)
12:54:14.166 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_21.tsv (88 / 163)
12:54:14.357 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_23.tsv (89 / 163)
12:54:14.552 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_26.tsv (90 / 163)
12:54:14.750 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_28.tsv (91 / 163)
12:54:14.943 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_29.tsv (92 / 163)
12:54:15.148 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_30.tsv (93 / 163)
12:54:15.352 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_32.tsv (94 / 163)
12:54:15.573 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_35.tsv (95 / 163)
12:54:15.756 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_39.tsv (96 / 163)
12:54:15.968 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_40.tsv (97 / 163)
12:54:16.549 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_42.tsv (98 / 163)
12:54:16.740 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_45.tsv (99 / 163)
12:54:16.928 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_46.tsv (100 / 163)
12:54:17.139 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_62.tsv (101 / 163)
12:54:17.333 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_65.tsv (102 / 163)
12:54:17.531 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_80.tsv (103 / 163)
12:54:17.735 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_91.tsv (104 / 163)
12:54:17.978 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4344_93.tsv (105 / 163)
12:54:18.171 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_06.tsv (106 / 163)
12:54:18.356 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_20.tsv (107 / 163)
12:54:18.728 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_28.tsv (108 / 163)
12:54:18.924 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_29.tsv (109 / 163)
12:54:19.114 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_37.tsv (110 / 163)
12:54:19.313 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_39.tsv (111 / 163)
12:54:19.512 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_46.tsv (112 / 163)
12:54:19.695 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_50.tsv (113 / 163)
12:54:19.889 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_53.tsv (114 / 163)
12:54:20.140 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_58.tsv (115 / 163)
12:54:20.348 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_60.tsv (116 / 163)
12:54:20.545 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_61.tsv (117 / 163)
12:54:20.752 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_65.tsv (118 / 163)
12:54:20.943 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_71.tsv (119 / 163)
12:54:21.136 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_81.tsv (120 / 163)
12:54:21.356 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_82.tsv (121 / 163)
12:54:21.558 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_83.tsv (122 / 163)
12:54:21.772 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_87.tsv (123 / 163)
12:54:21.962 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_90.tsv (124 / 163)
12:54:22.157 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4446_91.tsv (125 / 163)
12:54:22.383 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_01.tsv (126 / 163)
12:54:22.586 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_08.tsv (127 / 163)
12:54:22.811 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_11.tsv (128 / 163)
12:54:23.022 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_13.tsv (129 / 163)
12:54:23.243 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_18.tsv (130 / 163)
12:54:23.462 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_20.tsv (131 / 163)
12:54:23.664 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_23.tsv (132 / 163)
12:54:23.848 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_24.tsv (133 / 163)
12:54:24.046 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_25.tsv (134 / 163)
12:54:24.236 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_27.tsv (135 / 163)
12:54:24.424 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_28.tsv (136 / 163)
12:54:24.609 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_29.tsv (137 / 163)
12:54:24.825 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_31.tsv (138 / 163)
12:54:25.045 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_34.tsv (139 / 163)
12:54:25.241 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_35.tsv (140 / 163)
12:54:25.424 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_46.tsv (141 / 163)
12:54:25.627 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_48.tsv (142 / 163)
12:54:25.802 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_51.tsv (143 / 163)
12:54:25.986 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_52.tsv (144 / 163)
12:54:26.180 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_55.tsv (145 / 163)
12:54:26.374 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_58.tsv (146 / 163)
12:54:26.563 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_63.tsv (147 / 163)
12:54:26.770 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_65.tsv (148 / 163)
12:54:26.990 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_66.tsv (149 / 163)
12:54:27.218 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_67.tsv (150 / 163)
12:54:27.421 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_69.tsv (151 / 163)
12:54:27.599 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_70.tsv (152 / 163)
12:54:27.809 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_74.tsv (153 / 163)
12:54:27.991 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_75.tsv (154 / 163)
12:54:28.197 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_76.tsv (155 / 163)
12:54:28.388 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_77.tsv (156 / 163)
12:54:28.588 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_78.tsv (157 / 163)
12:54:28.796 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_82.tsv (158 / 163)
12:54:28.995 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_85.tsv (159 / 163)
12:54:29.197 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_86.tsv (160 / 163)
12:54:29.388 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_91.tsv (161 / 163)
12:54:29.570 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_92.tsv (162 / 163)
12:54:29.769 INFO GermlineCNVCaller - Aggregating read-count file /home/inos0304/human_genome_analysis/cnv/analysis_female/tsv/PG4482_93.tsv (163 / 163)
12:54:29.984 DEBUG ScriptExecutor - Executing:
12:54:29.984 DEBUG ScriptExecutor - python
12:54:29.984 DEBUG ScriptExecutor - /tmp/cohort_denoising_calling.7897284268644721648.py
12:54:29.984 DEBUG ScriptExecutor - --ploidy_calls_path=/rshare1/ZETTAI_path_WA_slash_home_KARA/home/inos0304/human_genome_analysis/cnv/analysis_female/ploidy-calls
12:54:29.984 DEBUG ScriptExecutor - --output_calls_path=/rshare1/ZETTAI_path_WA_slash_home_KARA/home/inos0304/human_genome_analysis/cnv/analysis_female/cohort_female/cohort_female_01-calls
12:54:29.985 DEBUG ScriptExecutor - --output_tracking_path=/rshare1/ZETTAI_path_WA_slash_home_KARA/home/inos0304/human_genome_analysis/cnv/analysis_female/cohort_female/cohort_female_01-tracking
12:54:29.985 DEBUG ScriptExecutor - --random_seed=1984
12:54:29.985 DEBUG ScriptExecutor - --modeling_interval_list=/tmp/intervals6686287929758062705.tsv
12:54:29.985 DEBUG ScriptExecutor - --output_model_path=/rshare1/ZETTAI_path_WA_slash_home_KARA/home/inos0304/human_genome_analysis/cnv/analysis_female/cohort_female/cohort_female_01-model
12:54:29.985 DEBUG ScriptExecutor - --enable_explicit_gc_bias_modeling=True
12:54:29.985 DEBUG ScriptExecutor - --read_count_tsv_files
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_04_L000.rc3951587632584113947.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_13_L000.rc2817140940332361158.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_17_L000.rc1353160991793239294.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_20_L000.rc5443290680079975178.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_23_L000.rc4202726641846501882.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_24_L000.rc3844372011522155562.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_25_L000.rc4211871239448496430.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_27_L000.rc2078571147927776793.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_29_L000.rc2312984411399163832.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_30_L000.rc2671859470812939841.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_31_L000.rc8131997912022436685.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_32_L000.rc5425924761380826027.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_36_L000.rc6077081999421275427.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_41_L000.rc4638880017656916034.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_47_L000.rc2179592229410555594.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_49_L000.rc4821910718672553988.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_56_L000.rc3585817649894912371.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_59_L000.rc4331814691458776405.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_60_L000.rc8417982606093213458.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_64_L000.rc6668246980776702645.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_67_L000.rc2676667985183619979.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_68_L000.rc1794788848788372038.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_85_L000.rc9042912601102939235.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_HN7448_01_a_86_L000.rc2652207305853661414.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_05_L000.rc1111206176752049324.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_07_L000.rc7105431395795554091.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_09_L000.rc5428672356749640673.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_18_L000.rc8229478461003434380.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_20_L000.rc4810986761376980399.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_28_L000.rc2384284316666061771.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_32_L000.rc7861634724068653184.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_34_L000.rc4204853300704529512.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_35_L000.rc6844750191396362839.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_39_L000.rc8002672096565237796.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_41_L000.rc1137860610266666648.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_44_L000.rc3171143126262253794.tsv
12:54:29.985 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_50_L000.rc7011748867762950617.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_56_L000.rc2753646992781650104.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_57_L000.rc606489262117838130.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_59_L000.rc851684893997579592.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_63_L000.rc7169492100184240653.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_73_L000.rc2787351745864609149.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_78_L000.rc5716756861494644029.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_92_L000.rc2137441952589913936.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/MACROGENS_JN6556_01_a_95_L000.rc8696648545731031379.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNWKVDSXY_PG4100_01_a_07_L001.rc8092308563994820453.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNWKVDSXY_PG4100_01_a_15_L001.rc613253478399407214.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNWKVDSXY_PG4100_01_a_16_L001.rc9118660059916664518.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNWKVDSXY_PG4100_01_a_23_L001.rc6773583503002125141.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNWKVDSXY_PG4100_01_a_25_L001.rc2029164227123734817.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNWKVDSXY_PG4100_01_a_31_L001.rc1672437625058768986.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNWKVDSXY_PG4100_01_a_37_L001.rc5011170813985009137.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNWKVDSXY_PG4100_01_a_43_L001.rc214536849684356150.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNWKVDSXY_PG4100_01_a_45_L001.rc2088461843657343218.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNWKVDSXY_PG4100_01_a_46_L001.rc6608157904977623379.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNWKVDSXY_PG4100_01_a_48_L001.rc8397835078346418111.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNWKVDSXY_PG4100_01_a_50_L001.rc7088661352140005377.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNWKVDSXY_PG4100_01_a_56_L001.rc7516295595985160954.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNWKVDSXY_PG4100_01_a_58_L001.rc1633620828004506686.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNWKVDSXY_PG4100_01_a_60_L001.rc3459926246738767901.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_03_L004.rc1544699126476654640.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_11_L004.rc8701139391591637730.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_16_L004.rc7265091205097035653.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_17_L004.rc7078160573973872162.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_21_L004.rc3384115793271128925.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_23_L004.rc4272558804190696863.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_29_L004.rc3406270535943325188.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_30_L004.rc8880942446235540722.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_33_L004.rc5787789947556885395.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_34_L004.rc8254006981823894376.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_41_L004.rc777724503250344569.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_43_L004.rc810086566455872122.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_52_L004.rc5294500601568685380.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_55_L004.rc594815798861214391.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_58_L004.rc6870952332611476492.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_61_L004.rc7305346801297675488.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_73_L004.rc7618359998248316828.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_77_L004.rc8801102784041877120.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_90_L004.rc8543182381532340835.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HNCCFDSXY_PG4213_01_a_96_L004.rc5613757984559731531.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_02_L003.rc9060982360343357017.tsv
12:54:29.986 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_07_L003.rc5679251610922898999.tsv
12:54:29.987 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_09_L003.rc5275868109922003313.tsv
12:54:29.987 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_10_L003.rc1366773845716946573.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_11_L003.rc8232290981762080452.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_12_L003.rc8339345692048573300.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_19_L003.rc5900047828306812145.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_21_L003.rc8156377833835540728.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_23_L003.rc42959568866036864.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_26_L003.rc8434713712820844094.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_28_L003.rc7203215237348512062.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_29_L003.rc4674770261106361504.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_30_L003.rc5322389575874734115.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_32_L003.rc8927967894789378203.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_35_L003.rc4860503731074248210.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_39_L003.rc7508312406042017413.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_40_L003.rc5262387860669136438.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_42_L003.rc949798095708877936.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_45_L003.rc974578986510147550.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_46_L003.rc2731204219838229404.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_62_L003.rc6031131594467053610.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_65_L003.rc5686231609551740393.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_80_L003.rc3797688145367021518.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_91_L003.rc6633033096651079038.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HYNWKDSXY_PG4344_01_a_93_L003.rc4068784655326701496.tsv
12:54:29.988 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_06_L003.rc75171311512305807.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_20_L003.rc8428199540919941009.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_28_L003.rc2454938050462352339.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_29_L003.rc6715947823202456266.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_37_L003.rc9177288614149244615.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_39_L003.rc8536316557077026286.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_46_L003.rc4038707486176834177.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_50_L003.rc1108725580972503433.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_53_L003.rc7966930746639168897.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_58_L003.rc7787918230122445158.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_60_L003.rc1745017445525676236.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_61_L003.rc1203992529574252929.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_65_L003.rc5355240559784398903.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_71_L003.rc6019297211299163794.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_81_L003.rc7438880056592234431.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_82_L003.rc8395282881772400033.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_83_L003.rc725100834105174829.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_87_L003.rc2310637225307992510.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_90_L003.rc8185573960692241242.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HL2WFDSX2_PG4446_01_a_91_L003.rc8721216208246830813.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_01_L002.rc4096525963468523075.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_08_L002.rc3877077002371659090.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_11_L002.rc2864445185458197198.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_13_L002.rc6766590653864943389.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_18_L002.rc6783546502924137756.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_20_L002.rc2668835601045195742.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_23_L002.rc27479877263449498.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_24_L002.rc8623004488533807753.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_25_L002.rc8928435576344215912.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_27_L002.rc821493315693280621.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_28_L002.rc315728919931511944.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_29_L002.rc2245488671200137356.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_31_L002.rc7536102176033986039.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_34_L002.rc7204601429431029134.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_35_L002.rc8163812312182142292.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_46_L002.rc3896110869651005079.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_48_L002.rc3846189428458233717.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_51_L002.rc3976483851212626670.tsv
12:54:29.989 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_52_L002.rc4555755135723076219.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_55_L002.rc5517749886337105144.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_58_L002.rc4550622138560177470.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_63_L002.rc4752717824772712822.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_65_L002.rc139534854162955232.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_66_L002.rc842027218534683306.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_67_L002.rc4597135044764632167.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_69_L002.rc6048306688849017341.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_70_L002.rc6517226226529420061.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_74_L002.rc196572769228029819.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_75_L002.rc490116393549817957.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_76_L002.rc4277028080765178474.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_77_L002.rc7367174451648432877.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_78_L002.rc916503889335873182.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_82_L002.rc8944143391850314976.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_85_L002.rc667154302528512491.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_86_L002.rc5008187721685497393.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_91_L002.rc7011770976962256032.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_92_L002.rc5255433541987261995.tsv
12:54:29.990 DEBUG ScriptExecutor - /tmp/HMCJWDSX2_PG4482_01_a_93_L002.rc6396810383002884095.tsv
12:54:29.990 DEBUG ScriptExecutor - --psi_s_scale=1.000000e-04
12:54:29.990 DEBUG ScriptExecutor - --mapping_error_rate=1.000000e-02
12:54:29.990 DEBUG ScriptExecutor - --depth_correction_tau=1.000000e+04
12:54:29.990 DEBUG ScriptExecutor - --q_c_expectation_mode=hybrid
12:54:29.990 DEBUG ScriptExecutor - --num_samples_copy_ratio_approx=200
12:54:29.990 DEBUG ScriptExecutor - --max_bias_factors=5
12:54:29.990 DEBUG ScriptExecutor - --psi_t_scale=1.000000e-03
12:54:29.990 DEBUG ScriptExecutor - --log_mean_bias_std=1.000000e-01
12:54:29.990 DEBUG ScriptExecutor - --init_ard_rel_unexplained_variance=1.000000e-01
12:54:29.990 DEBUG ScriptExecutor - --num_gc_bins=20
12:54:29.990 DEBUG ScriptExecutor - --gc_curve_sd=1.000000e+00
12:54:29.990 DEBUG ScriptExecutor - --active_class_padding_hybrid_mode=50000
12:54:29.990 DEBUG ScriptExecutor - --enable_bias_factors=True
12:54:29.990 DEBUG ScriptExecutor - --disable_bias_factors_in_active_class=False
12:54:29.990 DEBUG ScriptExecutor - --p_alt=1.000000e-06
12:54:29.990 DEBUG ScriptExecutor - --cnv_coherence_length=1.000000e+04
12:54:29.990 DEBUG ScriptExecutor - --max_copy_number=5
12:54:29.990 DEBUG ScriptExecutor - --p_active=0.010000
12:54:29.990 DEBUG ScriptExecutor - --class_coherence_length=10000.000000
12:54:29.990 DEBUG ScriptExecutor - --learning_rate=1.000000e-02
12:54:29.990 DEBUG ScriptExecutor - --adamax_beta1=9.000000e-01
12:54:29.990 DEBUG ScriptExecutor - --adamax_beta2=9.900000e-01
12:54:29.990 DEBUG ScriptExecutor - --log_emission_samples_per_round=50
12:54:29.990 DEBUG ScriptExecutor - --log_emission_sampling_rounds=10
12:54:29.990 DEBUG ScriptExecutor - --log_emission_sampling_median_rel_error=5.000000e-03
12:54:29.990 DEBUG ScriptExecutor - --max_advi_iter_first_epoch=5000
12:54:29.990 DEBUG ScriptExecutor - --max_advi_iter_subsequent_epochs=200
12:54:29.990 DEBUG ScriptExecutor - --min_training_epochs=10
12:54:29.990 DEBUG ScriptExecutor - --max_training_epochs=50
12:54:29.990 DEBUG ScriptExecutor - --initial_temperature=1.500000e+00
12:54:29.990 DEBUG ScriptExecutor - --num_thermal_advi_iters=2500
12:54:29.990 DEBUG ScriptExecutor - --convergence_snr_averaging_window=500
12:54:29.990 DEBUG ScriptExecutor - --convergence_snr_trigger_threshold=1.000000e-01
12:54:29.990 DEBUG ScriptExecutor - --convergence_snr_countdown_window=10
12:54:29.990 DEBUG ScriptExecutor - --max_calling_iters=10
12:54:29.990 DEBUG ScriptExecutor - --caller_update_convergence_threshold=1.000000e-03
12:54:29.991 DEBUG ScriptExecutor - --caller_internal_admixing_rate=7.500000e-01
12:54:29.991 DEBUG ScriptExecutor - --caller_external_admixing_rate=1.000000e+00
12:54:29.991 DEBUG ScriptExecutor - --disable_caller=false
12:54:29.991 DEBUG ScriptExecutor - --disable_sampler=false
12:54:29.991 DEBUG ScriptExecutor - --disable_annealing=false
13:23:10.459 INFO GermlineCNVCaller - Shutting down engine
[2022/04/22 13:23:10 JST] org.broadinstitute.hellbender.tools.copynumber.GermlineCNVCaller done. Elapsed time: 31.13 minutes.
Runtime.totalMemory()=6227755008
org.broadinstitute.hellbender.utils.python.PythonScriptExecutorException:
python exited with 135
Command Line: python /tmp/cohort_denoising_calling.7897284268644721648.py --ploidy_calls_path=/rshare1/ZETTAI_path_WA_slash_home_KARA/home/inos0304/human_genome_analysis/cnv/analysis_female/ploidy-calls --output_calls_path=/rshare1/ZETTAI_path_WA_slash_home_KARA/home/inos0304/human_genome_analysis/cnv/analysis_female/cohort_female/cohort_female_01-calls --output_tracking_path=/rshare1/ZETTAI_path_WA_slash_home_KARA/home/inos0304/human_genome_analysis/cnv/analysis_female/cohort_female/cohort_female_01-tracking --random_seed=1984 --modeling_interval_list=/tmp/intervals6686287929758062705.tsv --output_model_path=/rshare1/ZETTAI_path_WA_slash_home_KARA/home/inos0304/human_genome_analysis/cnv/analysis_female/cohort_female/cohort_female_01-model --enable_explicit_gc_bias_modeling=True --read_count_tsv_files /tmp/MACROGENS_HN7448_01_a_04_L000.rc3951587632584113947.tsv /tmp/MACROGENS_HN7448_01_a_13_L000.rc2817140940332361158.tsv /tmp/MACROGENS_HN7448_01_a_17_L000.rc1353160991793239294.tsv /tmp/MACROGENS_HN7448_01_a_20_L000.rc5443290680079975178.tsv /tmp/MACROGENS_HN7448_01_a_23_L000.rc4202726641846501882.tsv /tmp/MACROGENS_HN7448_01_a_24_L000.rc3844372011522155562.tsv /tmp/MACROGENS_HN7448_01_a_25_L000.rc4211871239448496430.tsv /tmp/MACROGENS_HN7448_01_a_27_L000.rc2078571147927776793.tsv /tmp/MACROGENS_HN7448_01_a_29_L000.rc2312984411399163832.tsv /tmp/MACROGENS_HN7448_01_a_30_L000.rc2671859470812939841.tsv /tmp/MACROGENS_HN7448_01_a_31_L000.rc8131997912022436685.tsv /tmp/MACROGENS_HN7448_01_a_32_L000.rc5425924761380826027.tsv /tmp/MACROGENS_HN7448_01_a_36_L000.rc6077081999421275427.tsv /tmp/MACROGENS_HN7448_01_a_41_L000.rc4638880017656916034.tsv /tmp/MACROGENS_HN7448_01_a_47_L000.rc2179592229410555594.tsv /tmp/MACROGENS_HN7448_01_a_49_L000.rc4821910718672553988.tsv /tmp/MACROGENS_HN7448_01_a_56_L000.rc3585817649894912371.tsv /tmp/MACROGENS_HN7448_01_a_59_L000.rc4331814691458776405.tsv /tmp/MACROGENS_HN7448_01_a_60_L000.rc8417982606093213458.tsv /tmp/MACROGENS_HN7448_01_a_64_L000.rc6668246980776702645.tsv /tmp/MACROGENS_HN7448_01_a_67_L000.rc2676667985183619979.tsv /tmp/MACROGENS_HN7448_01_a_68_L000.rc1794788848788372038.tsv /tmp/MACROGENS_HN7448_01_a_85_L000.rc9042912601102939235.tsv /tmp/MACROGENS_HN7448_01_a_86_L000.rc2652207305853661414.tsv /tmp/MACROGENS_JN6556_01_a_05_L000.rc1111206176752049324.tsv /tmp/MACROGENS_JN6556_01_a_07_L000.rc7105431395795554091.tsv /tmp/MACROGENS_JN6556_01_a_09_L000.rc5428672356749640673.tsv /tmp/MACROGENS_JN6556_01_a_18_L000.rc8229478461003434380.tsv /tmp/MACROGENS_JN6556_01_a_20_L000.rc4810986761376980399.tsv /tmp/MACROGENS_JN6556_01_a_28_L000.rc2384284316666061771.tsv /tmp/MACROGENS_JN6556_01_a_32_L000.rc7861634724068653184.tsv /tmp/MACROGENS_JN6556_01_a_34_L000.rc4204853300704529512.tsv /tmp/MACROGENS_JN6556_01_a_35_L000.rc6844750191396362839.tsv /tmp/MACROGENS_JN6556_01_a_39_L000.rc8002672096565237796.tsv /tmp/MACROGENS_JN6556_01_a_41_L000.rc1137860610266666648.tsv /tmp/MACROGENS_JN6556_01_a_44_L000.rc3171143126262253794.tsv /tmp/MACROGENS_JN6556_01_a_50_L000.rc7011748867762950617.tsv /tmp/MACROGENS_JN6556_01_a_56_L000.rc2753646992781650104.tsv /tmp/MACROGENS_JN6556_01_a_57_L000.rc606489262117838130.tsv /tmp/MACROGENS_JN6556_01_a_59_L000.rc851684893997579592.tsv /tmp/MACROGENS_JN6556_01_a_63_L000.rc7169492100184240653.tsv /tmp/MACROGENS_JN6556_01_a_73_L000.rc2787351745864609149.tsv /tmp/MACROGENS_JN6556_01_a_78_L000.rc5716756861494644029.tsv /tmp/MACROGENS_JN6556_01_a_92_L000.rc2137441952589913936.tsv /tmp/MACROGENS_JN6556_01_a_95_L000.rc8696648545731031379.tsv /tmp/HNWKVDSXY_PG4100_01_a_07_L001.rc8092308563994820453.tsv /tmp/HNWKVDSXY_PG4100_01_a_15_L001.rc613253478399407214.tsv /tmp/HNWKVDSXY_PG4100_01_a_16_L001.rc9118660059916664518.tsv /tmp/HNWKVDSXY_PG4100_01_a_23_L001.rc6773583503002125141.tsv /tmp/HNWKVDSXY_PG4100_01_a_25_L001.rc2029164227123734817.tsv /tmp/HNWKVDSXY_PG4100_01_a_31_L001.rc1672437625058768986.tsv /tmp/HNWKVDSXY_PG4100_01_a_37_L001.rc5011170813985009137.tsv /tmp/HNWKVDSXY_PG4100_01_a_43_L001.rc214536849684356150.tsv /tmp/HNWKVDSXY_PG4100_01_a_45_L001.rc2088461843657343218.tsv /tmp/HNWKVDSXY_PG4100_01_a_46_L001.rc6608157904977623379.tsv /tmp/HNWKVDSXY_PG4100_01_a_48_L001.rc8397835078346418111.tsv /tmp/HNWKVDSXY_PG4100_01_a_50_L001.rc7088661352140005377.tsv /tmp/HNWKVDSXY_PG4100_01_a_56_L001.rc7516295595985160954.tsv /tmp/HNWKVDSXY_PG4100_01_a_58_L001.rc1633620828004506686.tsv /tmp/HNWKVDSXY_PG4100_01_a_60_L001.rc3459926246738767901.tsv /tmp/HNCCFDSXY_PG4213_01_a_03_L004.rc1544699126476654640.tsv /tmp/HNCCFDSXY_PG4213_01_a_11_L004.rc8701139391591637730.tsv /tmp/HNCCFDSXY_PG4213_01_a_16_L004.rc7265091205097035653.tsv /tmp/HNCCFDSXY_PG4213_01_a_17_L004.rc7078160573973872162.tsv /tmp/HNCCFDSXY_PG4213_01_a_21_L004.rc3384115793271128925.tsv /tmp/HNCCFDSXY_PG4213_01_a_23_L004.rc4272558804190696863.tsv /tmp/HNCCFDSXY_PG4213_01_a_29_L004.rc3406270535943325188.tsv /tmp/HNCCFDSXY_PG4213_01_a_30_L004.rc8880942446235540722.tsv /tmp/HNCCFDSXY_PG4213_01_a_33_L004.rc5787789947556885395.tsv /tmp/HNCCFDSXY_PG4213_01_a_34_L004.rc8254006981823894376.tsv /tmp/HNCCFDSXY_PG4213_01_a_41_L004.rc777724503250344569.tsv /tmp/HNCCFDSXY_PG4213_01_a_43_L004.rc810086566455872122.tsv /tmp/HNCCFDSXY_PG4213_01_a_52_L004.rc5294500601568685380.tsv /tmp/HNCCFDSXY_PG4213_01_a_55_L004.rc594815798861214391.tsv /tmp/HNCCFDSXY_PG4213_01_a_58_L004.rc6870952332611476492.tsv /tmp/HNCCFDSXY_PG4213_01_a_61_L004.rc7305346801297675488.tsv /tmp/HNCCFDSXY_PG4213_01_a_73_L004.rc7618359998248316828.tsv /tmp/HNCCFDSXY_PG4213_01_a_77_L004.rc8801102784041877120.tsv /tmp/HNCCFDSXY_PG4213_01_a_90_L004.rc8543182381532340835.tsv /tmp/HNCCFDSXY_PG4213_01_a_96_L004.rc5613757984559731531.tsv /tmp/HYNWKDSXY_PG4344_01_a_02_L003.rc9060982360343357017.tsv /tmp/HYNWKDSXY_PG4344_01_a_07_L003.rc5679251610922898999.tsv /tmp/HYNWKDSXY_PG4344_01_a_09_L003.rc5275868109922003313.tsv /tmp/HYNWKDSXY_PG4344_01_a_10_L003.rc1366773845716946573.tsv /tmp/HYNWKDSXY_PG4344_01_a_11_L003.rc8232290981762080452.tsv /tmp/HYNWKDSXY_PG4344_01_a_12_L003.rc8339345692048573300.tsv /tmp/HYNWKDSXY_PG4344_01_a_19_L003.rc5900047828306812145.tsv /tmp/HYNWKDSXY_PG4344_01_a_21_L003.rc8156377833835540728.tsv /tmp/HYNWKDSXY_PG4344_01_a_23_L003.rc42959568866036864.tsv /tmp/HYNWKDSXY_PG4344_01_a_26_L003.rc8434713712820844094.tsv /tmp/HYNWKDSXY_PG4344_01_a_28_L003.rc7203215237348512062.tsv /tmp/HYNWKDSXY_PG4344_01_a_29_L003.rc4674770261106361504.tsv /tmp/HYNWKDSXY_PG4344_01_a_30_L003.rc5322389575874734115.tsv /tmp/HYNWKDSXY_PG4344_01_a_32_L003.rc8927967894789378203.tsv /tmp/HYNWKDSXY_PG4344_01_a_35_L003.rc4860503731074248210.tsv /tmp/HYNWKDSXY_PG4344_01_a_39_L003.rc7508312406042017413.tsv /tmp/HYNWKDSXY_PG4344_01_a_40_L003.rc5262387860669136438.tsv /tmp/HYNWKDSXY_PG4344_01_a_42_L003.rc949798095708877936.tsv /tmp/HYNWKDSXY_PG4344_01_a_45_L003.rc974578986510147550.tsv /tmp/HYNWKDSXY_PG4344_01_a_46_L003.rc2731204219838229404.tsv /tmp/HYNWKDSXY_PG4344_01_a_62_L003.rc6031131594467053610.tsv /tmp/HYNWKDSXY_PG4344_01_a_65_L003.rc5686231609551740393.tsv /tmp/HYNWKDSXY_PG4344_01_a_80_L003.rc3797688145367021518.tsv /tmp/HYNWKDSXY_PG4344_01_a_91_L003.rc6633033096651079038.tsv /tmp/HYNWKDSXY_PG4344_01_a_93_L003.rc4068784655326701496.tsv /tmp/HL2WFDSX2_PG4446_01_a_06_L003.rc75171311512305807.tsv /tmp/HL2WFDSX2_PG4446_01_a_20_L003.rc8428199540919941009.tsv /tmp/HL2WFDSX2_PG4446_01_a_28_L003.rc2454938050462352339.tsv /tmp/HL2WFDSX2_PG4446_01_a_29_L003.rc6715947823202456266.tsv /tmp/HL2WFDSX2_PG4446_01_a_37_L003.rc9177288614149244615.tsv /tmp/HL2WFDSX2_PG4446_01_a_39_L003.rc8536316557077026286.tsv /tmp/HL2WFDSX2_PG4446_01_a_46_L003.rc4038707486176834177.tsv /tmp/HL2WFDSX2_PG4446_01_a_50_L003.rc1108725580972503433.tsv /tmp/HL2WFDSX2_PG4446_01_a_53_L003.rc7966930746639168897.tsv /tmp/HL2WFDSX2_PG4446_01_a_58_L003.rc7787918230122445158.tsv /tmp/HL2WFDSX2_PG4446_01_a_60_L003.rc1745017445525676236.tsv /tmp/HL2WFDSX2_PG4446_01_a_61_L003.rc1203992529574252929.tsv /tmp/HL2WFDSX2_PG4446_01_a_65_L003.rc5355240559784398903.tsv /tmp/HL2WFDSX2_PG4446_01_a_71_L003.rc6019297211299163794.tsv /tmp/HL2WFDSX2_PG4446_01_a_81_L003.rc7438880056592234431.tsv /tmp/HL2WFDSX2_PG4446_01_a_82_L003.rc8395282881772400033.tsv /tmp/HL2WFDSX2_PG4446_01_a_83_L003.rc725100834105174829.tsv /tmp/HL2WFDSX2_PG4446_01_a_87_L003.rc2310637225307992510.tsv /tmp/HL2WFDSX2_PG4446_01_a_90_L003.rc8185573960692241242.tsv /tmp/HL2WFDSX2_PG4446_01_a_91_L003.rc8721216208246830813.tsv /tmp/HMCJWDSX2_PG4482_01_a_01_L002.rc4096525963468523075.tsv /tmp/HMCJWDSX2_PG4482_01_a_08_L002.rc3877077002371659090.tsv /tmp/HMCJWDSX2_PG4482_01_a_11_L002.rc2864445185458197198.tsv /tmp/HMCJWDSX2_PG4482_01_a_13_L002.rc6766590653864943389.tsv /tmp/HMCJWDSX2_PG4482_01_a_18_L002.rc6783546502924137756.tsv /tmp/HMCJWDSX2_PG4482_01_a_20_L002.rc2668835601045195742.tsv /tmp/HMCJWDSX2_PG4482_01_a_23_L002.rc27479877263449498.tsv /tmp/HMCJWDSX2_PG4482_01_a_24_L002.rc8623004488533807753.tsv /tmp/HMCJWDSX2_PG4482_01_a_25_L002.rc8928435576344215912.tsv /tmp/HMCJWDSX2_PG4482_01_a_27_L002.rc821493315693280621.tsv /tmp/HMCJWDSX2_PG4482_01_a_28_L002.rc315728919931511944.tsv /tmp/HMCJWDSX2_PG4482_01_a_29_L002.rc2245488671200137356.tsv /tmp/HMCJWDSX2_PG4482_01_a_31_L002.rc7536102176033986039.tsv /tmp/HMCJWDSX2_PG4482_01_a_34_L002.rc7204601429431029134.tsv /tmp/HMCJWDSX2_PG4482_01_a_35_L002.rc8163812312182142292.tsv /tmp/HMCJWDSX2_PG4482_01_a_46_L002.rc3896110869651005079.tsv /tmp/HMCJWDSX2_PG4482_01_a_48_L002.rc3846189428458233717.tsv /tmp/HMCJWDSX2_PG4482_01_a_51_L002.rc3976483851212626670.tsv /tmp/HMCJWDSX2_PG4482_01_a_52_L002.rc4555755135723076219.tsv /tmp/HMCJWDSX2_PG4482_01_a_55_L002.rc5517749886337105144.tsv /tmp/HMCJWDSX2_PG4482_01_a_58_L002.rc4550622138560177470.tsv /tmp/HMCJWDSX2_PG4482_01_a_63_L002.rc4752717824772712822.tsv /tmp/HMCJWDSX2_PG4482_01_a_65_L002.rc139534854162955232.tsv /tmp/HMCJWDSX2_PG4482_01_a_66_L002.rc842027218534683306.tsv /tmp/HMCJWDSX2_PG4482_01_a_67_L002.rc4597135044764632167.tsv /tmp/HMCJWDSX2_PG4482_01_a_69_L002.rc6048306688849017341.tsv /tmp/HMCJWDSX2_PG4482_01_a_70_L002.rc6517226226529420061.tsv /tmp/HMCJWDSX2_PG4482_01_a_74_L002.rc196572769228029819.tsv /tmp/HMCJWDSX2_PG4482_01_a_75_L002.rc490116393549817957.tsv /tmp/HMCJWDSX2_PG4482_01_a_76_L002.rc4277028080765178474.tsv /tmp/HMCJWDSX2_PG4482_01_a_77_L002.rc7367174451648432877.tsv /tmp/HMCJWDSX2_PG4482_01_a_78_L002.rc916503889335873182.tsv /tmp/HMCJWDSX2_PG4482_01_a_82_L002.rc8944143391850314976.tsv /tmp/HMCJWDSX2_PG4482_01_a_85_L002.rc667154302528512491.tsv /tmp/HMCJWDSX2_PG4482_01_a_86_L002.rc5008187721685497393.tsv /tmp/HMCJWDSX2_PG4482_01_a_91_L002.rc7011770976962256032.tsv /tmp/HMCJWDSX2_PG4482_01_a_92_L002.rc5255433541987261995.tsv /tmp/HMCJWDSX2_PG4482_01_a_93_L002.rc6396810383002884095.tsv --psi_s_scale=1.000000e-04 --mapping_error_rate=1.000000e-02 --depth_correction_tau=1.000000e+04 --q_c_expectation_mode=hybrid --num_samples_copy_ratio_approx=200 --max_bias_factors=5 --psi_t_scale=1.000000e-03 --log_mean_bias_std=1.000000e-01 --init_ard_rel_unexplained_variance=1.000000e-01 --num_gc_bins=20 --gc_curve_sd=1.000000e+00 --active_class_padding_hybrid_mode=50000 --enable_bias_factors=True --disable_bias_factors_in_active_class=False --p_alt=1.000000e-06 --cnv_coherence_length=1.000000e+04 --max_copy_number=5 --p_active=0.010000 --class_coherence_length=10000.000000 --learning_rate=1.000000e-02 --adamax_beta1=9.000000e-01 --adamax_beta2=9.900000e-01 --log_emission_samples_per_round=50 --log_emission_sampling_rounds=10 --log_emission_sampling_median_rel_error=5.000000e-03 --max_advi_iter_first_epoch=5000 --max_advi_iter_subsequent_epochs=200 --min_training_epochs=10 --max_training_epochs=50 --initial_temperature=1.500000e+00 --num_thermal_advi_iters=2500 --convergence_snr_averaging_window=500 --convergence_snr_trigger_threshold=1.000000e-01 --convergence_snr_countdown_window=10 --max_calling_iters=10 --caller_update_convergence_threshold=1.000000e-03 --caller_internal_admixing_rate=7.500000e-01 --caller_external_admixing_rate=1.000000e+00 --disable_caller=false --disable_sampler=false --disable_annealing=false
at org.broadinstitute.hellbender.utils.python.PythonExecutorBase.getScriptException(PythonExecutorBase.java:75)
at org.broadinstitute.hellbender.tools.copynumber.GermlineCNVCaller.doWork(GermlineCNVCaller.java:351)
at org.broadinstitute.hellbender.cmdline.CommandLineProgram.runTool(CommandLineProgram.java:140)
at org.broadinstitute.hellbender.cmdline.CommandLineProgram.instanceMainPostParseArgs(CommandLineProgram.java:192)
at org.broadinstitute.hellbender.cmdline.CommandLineProgram.instanceMain(CommandLineProgram.java:211)
at org.broadinstitute.hellbender.Main.runCommandLineProgram(Main.java:160)
at org.broadinstitute.hellbender.Main.mainEntry(Main.java:203)
at org.broadinstitute.hellbender.Main.main(Main.java:289)
Using GATK jar /rshare1/ZETTAI_path_WA_slash_home_KARA/home/inos0304/modules/gatk-4.2.5.0/gatk-package-4.2.5.0-local.jar
See forum topic details at forum guidelines page: https://gatk.broadinstitute.org/hc/en-us/articles/360053845952-Forum-Guidelines
-
Hi shun inoue,
Thank you for your patience, I had to look into this issue with my colleagues because python exited with 135 is an uncommon error with this tool. We think this is a potential memory issue and your operating system is terminating this job.
How much memory is available on these nodes? You might consider decreasing the Xmx value, so that there is more memory available for the python script.
There are examples in our gCNV WDLs for how to set up environment variables, check out these lines: https://github.com/broadinstitute/gatk/blob/b6a28d1a8c03e2b90fc944e09aa153dd571b9398/scripts/cnv_wdl/germline/cnv_germline_cohort_workflow.wdl#L586
Best,
Genevieve
-
Hi, Genevieve,
Thank you for your proposal.
I am analyzing in a local HPC of my institute. Previously, I specified 16 cores and 16GB each. Then, HPC manager send me a following alert.
"""The following user's job was stopped because it was using more CPU than required.
This job will be held and will not start running.
* jobid, ******; def_slot, 16; CPU usage, 5826 %; Wild Score, 0.99
A higher Wild Score indicates that your program is more likely to be lacking in control."""I asked the manager to solve this issue and they answered that I should specify the number of slot more than 60.
Next, I specified 60 cores and 4GB each.After that I encountered the error of this article. This is the whole story.
I am assuming that it is too large number of slots, so I wonder if I can restrict the number of slots or cores to use in the script.
Setting up environment variables is seemed to be the solution, but the articled you pointed says "export MKL_NUM_THREADS=~{default=8 cpu}".
Does this mean the maximum number of slots to use is 8?
I don't give anything MKL_NUM_THREADS and OMP_NUM_THREADS.
To require more larger size of memory (like 16G) may solve this problem, but it takes long to start analysis in my environment. I hope the other solution.
Best,
Shun
-
Hi Shun,
So when you got the error, you were giving each core 4GB each? Your Xmx value used is -Xmx6g, which is higher than the memory for each core. Try decreasing the Xmx value or increasing the memory for each core.
Best,
Genevieve
-
Hi Genevieve,
Exactly.
Thanks to your advice, I do not encounter any errors now.
As you pointed, i had to require larger memories, but requiring larger memories and cores takes too long to start analysis.
I added environment variables as you mentioned above (MKL_NUM_THREADS and OMP_NUM_THREADS=16) to my shell scripts, then my HPC did not say the above alert about the number of cores.
My issues was simply the size of memory and the number, your advice of environment variables in wdl was so helpful. I had better limit the number of cores and require larger memory from the beginning.
Thank you.
Shun
-
Glad it is working now! Thanks for the update.
Please sign in to leave a comment.
5 comments