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Variant Discovery in High-Throughput Sequencing Data

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Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size. Learn more

Error in building panel of normal in somatic copy number variation calling

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    Lei Yu

    Hello, I am running the pipeline to call the somatic copy number variation. There was an error when I tried to build the panel of normal and I attached the detailed information with this post. I would appreciate it a lot if anyone met a similar situation before can provide some suggestions. 

     

    Thanks

    Lei

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    Genevieve Brandt (she/her)

    Hi Lei Yu,

    Is that the end of the program log? I don't see any specific errors. I'm wondering if the task got killed by your computing platform or something else which is why it ended so suddenly.

    Let me know what you think.

    Best,

    Genevieve

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    Lei Yu

    Hello Genevieve,

    Thanks for your reply. I think the error is:

    undefined symbol: cblas_dspr: : : undefined symbol: cblas_dspr/tmp/jniloader4407124213937830663netlib-native_system-linux-x86_64.soundefined symbol: cblas_dsprjav        asymbol lookup error: : :
    undefined symbol: cblas_dsprsymbol lookup error/tmp/jniloader4407124213937830663netlib-native_system-linux-x86_64.so
    java
    : : : /tmp/jniloader4407124213937830663netlib-native_system-linux-x86_64.soundefined symbol: cblas_dsprsymbol lookup error
    : : undefined symbol: cblas_dspr/tmp/jniloader4407124213937830663netlib-native_system-linux-x86_64.so

    I searched the error online it might because the environment setting. But I am not sure how to sovle the error. Any suggestions?

    I appreciate your help a lot!

     

    Thanks

     

     

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    Genevieve Brandt (she/her)

    Thank you Lei Yu for the update.

    Could you try with the newest GATK version 4.2.6.0 to confirm if you are seeing this with the latest GATK changes? 

    Can you also give some details about your environment and operating system?

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