Genome Analysis Toolkit

Variant Discovery in High-Throughput Sequencing Data

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Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size. Learn more

If base quality scores set at 2 for clipped regions are restored to the original score with MergeBamAlignment, how will clipped regions not contribute to downstream analyses?



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