Genome Analysis Toolkit

Variant Discovery in High-Throughput Sequencing Data

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Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size. Learn more

alt_allele_in_normal vs normal LOD: Is alt_allele_in_normal redundant?


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    David Benjamin

    Cheng Yan alt_allele_in_normal is a filter from an old version of Mutect2.  Only the probabilistic normal artifact model remains.

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