How number of somatic variants in the sample affects Mutect2 results?
Hi, I am calling somatic variants from an artificial cell mixture using Mutect2. The sample contains many more somatic variants than somatic mutation events in human tissue. Will Mutect2 (Calling, Filter) consider each variant independently? Or will Mutect2 do a correction (e.g. Bonferroni correction) considering all variants? Thanks!
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