Genome Analysis Toolkit

Variant Discovery in High-Throughput Sequencing Data

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Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size. Learn more

CreateSomaticPanelOfNormals (BETA) workflow

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    Gökalp Çelik

    Hi Paulo Ricardo

    This tool has been used by our team under Terra premises to generate a PoN using very large number of samples with a custom wdl script that can handle all the forseeable edge cases during this process. It may not be easy for any user to perform this task and as we mentioned before it may not be necessary for you to generate a PoN when you are using inbred model organisms. 

    I hope this helps. 

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