Genome Analysis Toolkit

Variant Discovery in High-Throughput Sequencing Data

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Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size. Learn more

Before using GATK, do I need to use short-read error correction tools such as RACER or HiTEC?

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    Louis Bergelson

    Hello, 

    Those tools aren't part of our standard pipeline and shouldn't be necessary for human genome calling with GATK.  I don't have any knowledge about those tools so I can't really say if they would be helpful or not.  

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