Genome Analysis Toolkit

Variant Discovery in High-Throughput Sequencing Data

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Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size. Learn more

VariantRecalibrator Follow

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    Adrián Segura

    In case of wanting to detect oncological variants on tumor samples, what databases should I provide as --resource? Is it convenient to select vcfs from specific databases like COSMIC? Or is it better to choose only vcfs of known polymorphisms as shown in the examples?

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